HitPredict

Interactor 1: DAAF4 (Q8WXU2)
Dynein axonemal assembly factor 4 (Dyslexia susceptibility 1 candidate gene 1 protein)
Gene: DNAAF4

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	19423554, 26871637
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 420 Hs			1 303
+	Mm
		1246859 DAAF4_MOUSE (1-420): 4.96e-108: 326: 79.05		CHIP_MOUSE (1-303): 1.23e-67: 214: 97.37
+	Hs
		1264069 DAAF4_HUMAN (1-420): 1.5e-101: 309: 100.00		Q9BPW0_HUMAN (1-259): 2.98e-36: 137: 20.91
+	Hs
		672793 CDC27_HUMAN (40-419): 1.51e-44: 167: 13.52		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Dm
		1368585 Q9VJD4_DROME (274-411): 3.45e-40: 147: 31.94		Q9VJD4_DROME (19-202): 9.28e-42: 148: 25.54
+	Mm
		1141207 PPP5_MOUSE (269-419): 2.78e-38: 146: 23.18		PPP5_MOUSE (1-259): 7.23e-36: 136: 20.91
+	Hs
		858598 PPP5_HUMAN (269-419): 9.35e-38: 145: 23.18		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Ps
		1341481 TOC64_PEA (287-414): 1.2e-38: 148: 32.81		TOC64_PEA (4-137): 3.99e-33: 129: 28.36
+	Hs
		213621 SGTB_HUMAN (240-420): 1.13e-39: 145: 23.04		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Rn
		251112 SGTA_RAT (243-416): 1.58e-38: 143: 21.58		SGTA_RAT (3-140): 5.31e-33: 125: 28.99
+	Hs
		858652 PPP5_HUMAN (269-419): 9.35e-38: 145: 23.18		WDTC1_HUMAN (21-272): 3.45e-30: 122: 18.82
+	Hs
		213414 SGTA_HUMAN (243-416): 2.65e-37: 139: 23.16		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Mm
		1206764 SGTA_MOUSE (243-416): 1.04e-37: 140: 21.47		SGTA_MOUSE (4-140): 2.54e-32: 123: 28.47
+	Hs
		685025 STIP1_HUMAN (287-418): 3.89e-23: 103: 25.00		UN45A_HUMAN (15-161): 8.39e-42: 155: 29.30
+	Hs
		1234379 UN45A_HUMAN (272-412): 7.08e-33: 133: 29.86		WDTC1_HUMAN (21-272): 3.45e-30: 122: 18.82
+	Hs
		684549 STIP1_HUMAN (287-418): 3.89e-23: 103: 25.00		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		213490 STIP1_HUMAN (287-418): 3.89e-23: 103: 25.00		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Dm
		1366835 Q9VH81_DROME (257-419): 2.97e-37: 143: 22.70		Q9VPN5_DROME (26-202): 1.32e-15: 78.6: 17.30
+	Hs
		1290144 SGTB_HUMAN (240-420): 1.13e-39: 145: 23.04		SGTB_HUMAN (70-177): 7.78e-10: 60.8: 18.52
+	Hs
		1078491 UN45A_HUMAN (272-412): 7.08e-33: 133: 29.86		TOM34_HUMAN (26-117): 9.37e-11: 63.5: 35.87