HitPredict

Interactor 1: MYLIP (Q8WY64)
E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP)
Gene: MYLIP

Interactor 2: MYLIP (Q8WY64)
E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP)
Gene: MYLIP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.913

The method score is based on:

Property Details
Experiments 30079210, 29707137, 12826659, 21685362
Identification Methods two hybrid, pull down, enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FERM_C~FERM_C, FERM_C~FERM_M, FERM_C~FERM_N, FERM_M~FERM_M, FERM_M~FERM_N, FERM_N~FERM_N, zf-C3HC4_3~zf-C3HC4_3
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0006511 - ubiquitin-dependent protein catabolic process
and 11 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 445
Hs

1 445
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024