Interactor 1: ING5 (Q8WYH8)
Inhibitor of growth protein 5 (p28ING5)
Gene: ING5

Interactor 2: JADE2 (Q9NQC1)
E3 ubiquitin-protein ligase Jade-2 (EC 2.3.2.27) (Jade family PHD finger protein 2) (PHD finger protein 15)
Gene: JADE2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 25416956, 26186194, 21516116, 28514442, 30833792, 32296183, 33961781, 24981860, 16387653
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EPL1~ING
Common GO terms GO:0000123 - histone acetyltransferase complex
GO:0001558 - regulation of cell growth
GO:0005654 - nucleoplasm
GO:0006275 - regulation of DNA replication
GO:0006355 - regulation of DNA-templated transcription
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 240
Hs

1 790
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024