HitPredict

Interactor 1: RIN2 (Q8WYP3)
Ras and Rab interactor 2 (Ras association domain family 4) (Ras inhibitor JC265) (Ras interaction/interference protein 2)
Gene: RIN2

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 895 Hs			1 530
+	Hs
		1061942 GAPD1_HUMAN (215-755): 1.75e-79: 284: 13.20		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370663 RABX5_HUMAN (393-781): 9.51e-82: 274: 14.50		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1269396 ANR27_HUMAN (496-763): 1.58e-56: 213: 17.04		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1243831 KMT2C_HUMAN (157-510): 5.41e-48: 188: 10.87		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		433435 YES_HUMAN (37-218): 3.53e-41: 161: 19.25		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370040 KMT2C_HUMAN (157-510): 5.41e-48: 188: 10.87		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368834 YES_HUMAN (37-218): 3.53e-41: 161: 19.25		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		101828 F8WI37_MOUSE (157-510): 5.72e-64: 237: 13.43		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Mm
		1142676 KMT2C_MOUSE (157-510): 5.72e-64: 237: 13.43		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Hs
		368894 SRC_HUMAN (37-218): 4.05e-36: 146: 19.79		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		782595 KMT2C_HUMAN (157-510): 5.41e-48: 188: 10.87		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377007 FYN_HUMAN (37-218): 4.85e-50: 187: 19.79		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377057 SRC_HUMAN (37-218): 4.05e-36: 146: 19.79		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487890 SRC_HUMAN (37-218): 4.05e-36: 146: 19.79		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Hs
		487596 KMT2C_HUMAN (157-510): 5.41e-48: 188: 10.87		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		433225 YES_HUMAN (37-218): 3.53e-41: 161: 19.25		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		414427 SRC_HUMAN (37-218): 4.05e-36: 146: 19.79		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		454790 FGR_HUMAN (37-218): 1.12e-38: 153: 17.65		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487245 BLK_HUMAN (48-209): 1.23e-36: 147: 18.02		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487088 SRC_HUMAN (37-218): 4.05e-36: 146: 19.79		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59