HitPredict

Interactor 1: DGCR8 (Q8WYQ5)
Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8)
Gene: DGCR8

Interactor 2: DDX24 (Q9GZR7)
ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24)
Gene: DDX24

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Helicase_C~dsrm
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 773 Hs			1 859
+	Hs
		571528 DGCR8_HUMAN (1-773): 0: 1426: 100.00		DDX5_HUMAN (232-774): 1.14e-121: 382: 19.89
+	Hs
		1264672 DGCR8_HUMAN (1-773): 0: 1426: 100.00		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69
+	Hs
		1264621 DGCR8_HUMAN (1-773): 0: 1426: 100.00		DDX17_HUMAN (130-267): 9.12e-12: 70.9: 21.43
+	Mm
		1119392 DGCR8_MOUSE (1-773): 0: 1420: 95.34		DDX17_MOUSE (130-267): 1.79e-11: 69.7: 21.43