HitPredict

Interactor 1: RPGF4 (Q8WZA2)
Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII)
Gene: RAPGEF4

Interactor 2: SWP70 (Q9UH65)
Switch-associated protein 70 (SWAP-70)
Gene: SWAP70

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.628

The method score is based on:

Property Details
Experiments 24722188, 32814053
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1011
Hs

1 585
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024