Interactor 1: RPGF4 (Q8WZA2)
Rap guanine nucleotide exchange factor 4 (Exchange factor directly activated by cAMP 2) (Exchange protein directly activated by cAMP 2) (EPAC 2) (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII)
Gene: RAPGEF4

Interactor 2: RIMS2 (Q9UQ26)
Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3)
Gene: RIMS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 14660679, 11598134
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0017156 - calcium-ion regulated exocytosis
GO:0017157 - regulation of exocytosis
GO:0030073 - insulin secretion
GO:0031267 - small GTPase binding
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1011
Hs

1 1411
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024