Interactor 1: LRP5 (Q91VN0)
Low-density lipoprotein receptor-related protein 5 (LRP-5) (Low-density lipoprotein receptor-related protein 7) (LRP-7)
Gene: LRP5

Interactor 2: SOST (Q99P68)
Sclerostin
Gene: SOST

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17002572
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ldl_recept_b~Sclerostin
Common GO terms GO:0045893 - positive regulation of DNA-templated transcription
GO:0060070 - canonical Wnt signaling pathway
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1614
Mm

1 211
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024