HitPredict

Interactor 1: SHRPN (Q91WA6)
Sharpin (Shank-associated RH domain-interacting protein) (Shank-interacting protein-like 1) (mSIPL1)
Gene: Sharpin

Interactor 2: HOIL1 (Q9WUB0)
RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (Heme-oxidized IRP2 ubiquitin ligase 1 homolog) (HOIL-1) (RING-type E3 ubiquitin transferase HOIL-1) (UbcM4-interacting protein 28) (Ubiquitin-conjugating enzyme 7-interacting protein 3)
Gene: Rbck1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.696

The method score is based on:

Property Details
Experiments 29694895, 21455181, 21455180, 23942237
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, molecular sieving
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0042742 - defense response to bacterium
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0043130 - ubiquitin binding
and 4 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 380
Mm

1 508
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024