HitPredict

Interactor 1: MK08 (Q91Y86)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: Mapk8

Interactor 2: JIP1 (Q9WVI9)
C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain-1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1)
Gene: Mapk8ip1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 17709393, 11723054
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006355 - regulation of DNA-templated transcription
GO:0007254 - JNK cascade
and 5 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 384
Mm

1 707
+ Rn
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024