HitPredict

Interactor 1: SRGP1 (Q91Z69)
SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13)
Gene: Srgap1

Interactor 2: RHOA (Q9QUI0)
Transforming protein RhoA (EC 3.6.5.2)
Gene: RHOA

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11672528
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0007266 - Rho protein signal transduction GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1062 Mm			1 193
+	Hs
		900637 SRGP1_HUMAN (1-1062): 0: 680: 93.92		RHOA_HUMAN (1-193): 6.94e-79: 235: 99.48
+	Mm
		892733 SRGP1_MOUSE (1-1062): 0: 688: 100.00		CDC42_MOUSE (1-193): 5.57e-75: 225: 52.33
+	Hs
		925395 SRGP1_HUMAN (1-1062): 0: 680: 93.92		RAC1_HUMAN (1-193): 9.27e-78: 232: 57.22
+	Hs
		253337 SRGP2_HUMAN (1-1062): 0: 606: 67.07		RAC1_HUMAN (1-193): 9.27e-78: 232: 57.22
+	Hs
		253333 SRGP2_HUMAN (1-1062): 0: 606: 67.07		RAC3_HUMAN (1-179): 7.84e-72: 217: 57.54
+	Hs
		200213 SRGP3_HUMAN (1-1024): 0: 590: 66.10		RAC1_HUMAN (1-193): 9.27e-78: 232: 57.22
+	Hs
		925192 RHG04_HUMAN (1-911): 5.41e-133: 428: 41.33		RAC1_HUMAN (1-193): 9.27e-78: 232: 57.22
+	Dm
		776916 CDGAP_DROME (443-1053): 8.81e-107: 369: 18.66		RAC1_DROME (1-193): 1.89e-75: 226: 54.12
+	Hs
		900997 GMIP_HUMAN (44-859): 7.33e-90: 311: 15.44		RHOA_HUMAN (1-193): 6.94e-79: 235: 99.48
+	Hs
		925688 GMIP_HUMAN (44-859): 7.33e-90: 311: 15.44		RAC1_HUMAN (1-193): 9.27e-78: 232: 57.22
+	Hs
		925420 RHG12_HUMAN (375-671): 1.69e-88: 305: 25.33		RAC1_HUMAN (1-193): 9.27e-78: 232: 57.22
+	Hs
		894533 GMIP_HUMAN (44-859): 7.33e-90: 311: 15.44		CDC42_HUMAN (1-193): 5.57e-75: 225: 52.33
+	Hs
		900540 RHG29_HUMAN (44-1013): 2.06e-83: 297: 14.14		RHOA_HUMAN (1-193): 6.94e-79: 235: 99.48
+	Hs
		245183 OPHN1_HUMAN (115-896): 3.62e-85: 294: 15.93		RHOA_HUMAN (1-193): 6.94e-79: 235: 99.48
+	Hs
		245184 OPHN1_HUMAN (115-896): 3.62e-85: 294: 15.93		RAC1_HUMAN (1-193): 9.27e-78: 232: 57.22
+	Hs
		915815 RHG12_HUMAN (375-671): 1.69e-88: 305: 25.33		RHOB_HUMAN (1-191): 1.08e-71: 216: 83.94
+	Hs
		245182 OPHN1_HUMAN (115-896): 3.62e-85: 294: 15.93		CDC42_HUMAN (1-193): 5.57e-75: 225: 52.33
+	Hs
		63065 RHG42_HUMAN (115-958): 1.73e-84: 294: 13.52		RAC2_HUMAN (1-193): 1.61e-74: 224: 53.61
+	Hs
		915721 RHG29_HUMAN (44-1013): 2.06e-83: 297: 14.14		RHOB_HUMAN (1-191): 1.08e-71: 216: 83.94
+	Hs
		63072 RHG42_HUMAN (115-958): 1.73e-84: 294: 13.52		RAC3_HUMAN (1-179): 7.84e-72: 217: 57.54