HitPredict

Interactor 1: RAB4B (Q91ZR1)
Ras-related protein Rab-4B (EC 3.6.5.2)
Gene: RAB4B

Interactor 2: AFAD (Q9QZQ1)
Afadin (Afadin adherens junction formation factor) (Protein Af-6)
Gene: Afdn

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	26885862
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	DIL~Ras, PDZ~Ras, RA~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 213 Mm			1 1820
+	Hs
		231449 RAB4A_HUMAN (1-213): 1.11e-88: 261: 86.85		KIF1B_HUMAN (41-777): 4.56e-131: 454: 12.95
+	Hs
		592030 RAB4A_HUMAN (1-213): 1.11e-88: 261: 86.85		KI13B_HUMAN (41-690): 1.14e-101: 365: 12.85
+	Hs
		592005 RAB4A_HUMAN (1-213): 1.11e-88: 261: 86.85		KI13A_HUMAN (41-683): 4.17e-100: 360: 13.49
+	Hs
		914382 RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29		KI13B_HUMAN (41-690): 1.14e-101: 365: 12.85
+	Hs
		914346 RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29		KI13A_HUMAN (41-683): 4.17e-100: 360: 13.49
+	Rn
		914521 RB11A_RAT (2-211): 5.1e-86: 255: 44.29		MYO5B_RAT (53-933): 2.47e-99: 358: 13.57
+	Hs
		914453 RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29		MYO5B_HUMAN (53-933): 1.93e-93: 339: 13.12
+	Dm
		1197040 Q86BK8_DROME (4-213): 1.89e-91: 269: 57.14		KL98A_DROME (41-633): 7.69e-88: 317: 14.03
+	Hs
		895083 RAB2A_HUMAN (4-192): 2.82e-88: 260: 55.03		KIF14_HUMAN (38-688): 1.86e-87: 319: 14.80
+	Hs
		918872 RAB1A_HUMAN (1-211): 3.21e-87: 257: 40.28		KIF14_HUMAN (38-688): 1.86e-87: 319: 14.80
+	Hs
		1066669 RAB1B_HUMAN (1-211): 1.77e-86: 255: 39.81		KIF14_HUMAN (38-688): 1.86e-87: 319: 14.80
+	Hs
		896623 RAB14_HUMAN (4-213): 1.21e-85: 254: 58.10		KIF14_HUMAN (38-688): 1.86e-87: 319: 14.80
+	Hs
		914066 RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29		SCRIB_HUMAN (989-1132): 4.28e-22: 106: 27.03
+	Hs
		895319 RAB2A_HUMAN (4-192): 2.82e-88: 260: 55.03		NEB1_HUMAN (1002-1092): 1.08e-19: 98.7: 40.00
+	Hs
		592082 RAB4A_HUMAN (1-213): 1.11e-88: 261: 86.85		MYO5A_HUMAN (1343-1817): 5.8e-17: 90: 11.78
+	Hs
		895333 RAB2A_HUMAN (4-192): 2.82e-88: 260: 55.03		MYO5A_HUMAN (1343-1817): 5.8e-17: 90: 11.78
+	Hs
		914486 RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29		MYO5A_HUMAN (1343-1817): 5.8e-17: 90: 11.78
+	Hs
		591979 RAB4A_HUMAN (1-213): 1.11e-88: 261: 86.85		KI16B_HUMAN (1414-1814): 7.24e-11: 69.9: 11.58
+	Hs
		914285 RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29		KI16B_HUMAN (1414-1814): 7.24e-11: 69.9: 11.58
+	Hs
		914383 RB11A_HUMAN (2-211): 5.1e-86: 255: 44.29		MYO5C_HUMAN (1244-1730): 6.19e-10: 66.8: 12.93