HitPredict

Interactor 1: SMCA5 (Q91ZW3)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h)
Gene: Smarca5

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005677 - chromatin silencing complex GO:0031491 - nucleosome binding GO:1990830 - cellular response to leukemia inhibitory factor
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1051 Mm			1 441
+	Hs
		229258 SMCA5_HUMAN (22-1051): 0: 1081: 97.77		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1161361 SMCA1_MOUSE (23-1028): 0: 1032: 81.50		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		267906 SMCA1_HUMAN (67-1028): 0: 1020: 85.11		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		658714 SMCA1_HUMAN (67-1028): 0: 1020: 85.11		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		658715 SMCA1_HUMAN (67-1028): 0: 1020: 85.11		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		268053 CHD3_HUMAN (8-1051): 0: 808: 27.44		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		57194 CHD7_MOUSE (55-1046): 0: 794: 26.28		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268093 CHD4_HUMAN (2-944): 0: 768: 27.06		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1161077 CHD4_MOUSE (2-944): 0: 767: 27.06		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		1018633 CHD3_HUMAN (8-1051): 0: 808: 27.44		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		1018714 CHD3_HUMAN (8-1051): 0: 808: 27.44		NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09
+	Hs
		1059779 CHD4_HUMAN (2-944): 0: 768: 27.06		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1254435 CHD6_HUMAN (55-1038): 0: 752: 26.89		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		197011 CHD3_HUMAN (8-1051): 0: 808: 27.44		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51
+	Hs
		1309165 CHD8_HUMAN (6-1036): 0: 760: 25.97		TBL1Y_HUMAN (277-439): 5.06e-19: 91.1: 13.33
+	Hs
		151440 CHD1_HUMAN (29-1048): 0: 730: 28.36		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		903234 CHD4_HUMAN (2-944): 0: 768: 27.06		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		903535 CHD8_HUMAN (6-1036): 0: 760: 25.97		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		1336307 CHD8_HUMAN (6-1036): 0: 760: 25.97		FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97
+	Hs
		197020 CHD4_HUMAN (2-944): 0: 768: 27.06		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51