HitPredict

Interactor 1: LRP1 (Q91ZX7)
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
Gene: LRP1

Interactor 2: SYJ2B (Q9D6K5)
Synaptojanin-2-binding protein (Activin receptor-interacting protein 2) (Activin receptor-interacting protein 4) (Mitochondrial outer membrane protein 25)
Gene: Synj2bp

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	10827173
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 4545 Mm			1 145
+	Mm
		1143471 LRP1_MOUSE (19-4545): 0: 3530: 100.00		DLG4_MOUSE (3-135): 9.49e-28: 108: 30.83
+	Hs
		883911 LRP8_HUMAN (4063-4405): 1.7e-12: 76.4: 13.26		SYJ2B_HUMAN (1-145): 1.53e-48: 154: 91.03
+	Hs
		883907 LRP2_HUMAN (27-263): 7.99e-11: 71.4: 19.03		SYJ2B_HUMAN (1-145): 1.53e-48: 154: 91.03
+	Mm
		57561 LRP2_MOUSE (4063-4378): 2.31e-10: 69.9: 11.54		SYJ2B_MOUSE (1-145): 2.64e-48: 153: 100.00
+	Hs
		883908 LRP1_HUMAN (17-261): 9.34e-10: 67.9: 16.60		SYJ2B_HUMAN (1-145): 1.53e-48: 154: 91.03
+	Mm
		1267815 LRP1B_MOUSE (3369-3530): 9.59e-10: 67.9: 23.67		SNTG2_MOUSE (3-144): 2.72e-33: 123: 24.68
+	Hs
		942339 LRP8_HUMAN (4063-4405): 1.7e-12: 76.4: 13.26		DLG4_HUMAN (3-135): 9.13e-28: 108: 30.83
+	Hs
		957608 LRP2_HUMAN (27-263): 7.99e-11: 71.4: 19.03		DLG2_HUMAN (6-140): 8.2e-28: 109: 31.11
+	Dm
		113371 Q9VBN2_DROME (26-261): 6.1e-10: 67.9: 20.80		M9NFI9_DROME (14-109): 5.35e-29: 112: 31.96
+	Mm
		69882 B1AXJ3_MOUSE (3256-3451): 4.34e-11: 71.8: 16.67		DLG4_MOUSE (3-135): 9.49e-28: 108: 30.83
+	Hs
		942324 LRP2_HUMAN (27-263): 7.99e-11: 71.4: 19.03		DLG4_HUMAN (3-135): 9.13e-28: 108: 30.83
+	Dm
		113773 Q9W4Y3_DROME (28-105): 2.02e-09: 66.6: 42.31		M9NFI9_DROME (14-109): 5.35e-29: 112: 31.96
+	Mm
		57225 NID1_MOUSE (3451-3674): 4.26e-09: 65.2: 12.81		A2AKD7_MOUSE (1-141): 2.12e-29: 113: 23.08
+	Mm
		57555 LRP2_MOUSE (4063-4378): 2.31e-10: 69.9: 11.54		DLG4_MOUSE (3-135): 9.49e-28: 108: 30.83
+	Hs
		942331 LRP1_HUMAN (17-261): 9.34e-10: 67.9: 16.60		DLG4_HUMAN (3-135): 9.13e-28: 108: 30.83
+	Mm
		1143476 LRP8_MOUSE (24-285): 9.75e-10: 67.2: 19.33		DLG4_MOUSE (3-135): 9.49e-28: 108: 30.83
+	Hs
		957631 LRP2_HUMAN (27-263): 7.99e-11: 71.4: 19.03		DLG3_HUMAN (1-117): 5.97e-24: 98.1: 41.03