HitPredict

Interactor 1: EED (Q921E6)
Polycomb protein EED
Gene: EED

Interactor 2: ROAA (Q99020)
Heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) (CArG-binding factor-A) (CBF-A)
Gene: Hnrnpab

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20064375
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Mm			1 285
+	Hs
		161914 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		HNRDL_HUMAN (37-285): 3.81e-84: 260: 47.59
+	Mm
		1141204 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		HNRPD_MOUSE (60-285): 5.61e-82: 252: 53.58
+	Hs
		268080 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		HNRPD_HUMAN (60-285): 1.32e-81: 251: 53.24
+	Mm
		1206365 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		ROA3_MOUSE (48-241): 6.93e-80: 247: 37.81
+	Hs
		267964 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		ROA3_HUMAN (48-241): 6.73e-80: 247: 37.81
+	Hs
		267856 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		ROA1_HUMAN (63-240): 1.86e-79: 246: 38.92
+	Mm
		825791 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		ROA1_MOUSE (63-240): 1.14e-78: 242: 38.92
+	Hs
		268243 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		ROAA_HUMAN (1-285): 4.51e-64: 205: 71.89
+	Mm
		665768 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PABP1_MOUSE (4-140): 2.23e-30: 121: 16.00
+	Hs
		267888 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		ROA2_HUMAN (24-155): 1.52e-20: 91.6: 28.03
+	Mm
		291921 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		ROA2_MOUSE (24-155): 1.52e-20: 91.6: 28.03
+	Hs
		1048172 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		HNRPD_HUMAN (60-285): 1.32e-81: 251: 53.24
+	Hs
		852125 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		ROA3_HUMAN (48-241): 6.73e-80: 247: 37.81
+	Hs
		453519 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		ROA1_HUMAN (63-240): 1.86e-79: 246: 38.92
+	Hs
		162112 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		HNRDL_HUMAN (37-285): 3.81e-84: 260: 47.59
+	Hs
		1048176 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		HNRPD_HUMAN (60-285): 1.32e-81: 251: 53.24
+	Hs
		852133 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		ROA3_HUMAN (48-241): 6.73e-80: 247: 37.81
+	Hs
		453525 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		ROA1_HUMAN (63-240): 1.86e-79: 246: 38.92
+	Hs
		609988 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		ROA2_HUMAN (24-155): 1.52e-20: 91.6: 28.03
+	Hs
		609995 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		ROA2_HUMAN (24-155): 1.52e-20: 91.6: 28.03