HitPredict

Interactor 1: EED (Q921E6)
Polycomb protein EED
Gene: EED

Interactor 2: MTREX (Q9CZU3)
Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase)
Gene: MTREX

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DSHCT~WD40
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 Mm			1 1040
+	Hs
		267941 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		MTREX_HUMAN (1-1040): 0: 887: 97.31
+	Hs
		786997 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		MTREX_HUMAN (1-1040): 0: 887: 97.31
+	Hs
		267814 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		U520_HUMAN (111-841): 2.84e-102: 356: 17.28
+	Mm
		93330 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		ASCC3_MOUSE (24-811): 2.66e-98: 344: 16.35
+	Hs
		267880 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		DDX5_HUMAN (22-567): 8.56e-97: 321: 11.07
+	Mm
		1207263 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		Q8BTS0_MOUSE (19-567): 1.42e-96: 320: 11.19
+	Mm
		1161361 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SMCA1_MOUSE (6-860): 6.46e-90: 313: 11.86
+	Mm
		1265290 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SMCA5_MOUSE (11-860): 4.88e-89: 310: 11.67
+	Hs
		268206 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		DDX17_HUMAN (54-566): 1.62e-91: 310: 10.65
+	Mm
		1119389 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		DDX17_MOUSE (45-566): 4.75e-92: 309: 10.48
+	Hs
		229258 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		SMCA5_HUMAN (13-860): 8.99e-88: 306: 11.69
+	Hs
		272231 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		U520_HUMAN (111-841): 2.84e-102: 356: 17.28
+	Hs
		1232187 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		ASCC3_HUMAN (24-811): 1.47e-95: 336: 15.67
+	Hs
		272239 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		U520_HUMAN (111-841): 2.84e-102: 356: 17.28
+	Hs
		272085 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		U520_HUMAN (111-841): 2.84e-102: 356: 17.28
+	Hs
		1271615 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		DDX17_HUMAN (54-566): 1.62e-91: 310: 10.65
+	Hs
		571547 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		DDX5_HUMAN (22-567): 8.56e-97: 321: 11.07
+	Hs
		1271621 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		DDX17_HUMAN (54-566): 1.62e-91: 310: 10.65
+	Hs
		1271679 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		DDX17_HUMAN (54-566): 1.62e-91: 310: 10.65
+	Hs
		571382 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		DDX5_HUMAN (22-567): 8.56e-97: 321: 11.07