HitPredict

Interactor 1: EED (Q921E6)
Polycomb protein EED
Gene: EED

Interactor 2: SRS10 (Q9R0U0)
Serine/arginine-rich splicing factor 10 (FUS-interacting serine-arginine-rich protein 1) (Neural-salient serine/arginine-rich protein) (Neural-specific SR protein) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: Srsf10

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 441 Mm			1 262
+	Hs
		266873 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00
+	Hs
		268026 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79
+	Mm
		952209 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		SRSF3_MOUSE (1-95): 1.17e-25: 100: 35.79
+	Hs
		268033 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65
+	Mm
		665768 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		PABP1_MOUSE (2-99): 6.34e-19: 87.9: 17.35
+	Hs
		964033 POC1B_HUMAN (186-440): 4.25e-48: 173: 15.56		SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65
+	Hs
		267038 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00
+	Hs
		267045 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00
+	Hs
		964042 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65
+	Hs
		1288389 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46
+	Hs
		266949 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00
+	Hs
		952072 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79
+	Hs
		952150 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79
+	Hs
		903196 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37
+	Hs
		516438 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35
+	Hs
		1031492 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37
+	Hs
		516733 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35