HitPredict

Interactor 1: EED (Q921E6)
Polycomb protein EED
Gene: EED

Interactor 2: MTA2 (Q9R190)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1)
Gene: MTA2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MTA_R1~WD40
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071514 - genomic imprinting
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 441 Mm			1 668
+	Hs
		267823 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		MTA2_HUMAN (1-668): 0: 728: 98.50
+	Hs
		268070 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		MTA1_HUMAN (1-668): 0: 672: 55.83
+	Mm
		1225268 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		MTA1_MOUSE (1-668): 0: 664: 55.97
+	Hs
		268255 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		MTA3_HUMAN (1-567): 0: 643: 64.74
+	Mm
		1265395 EED_MOUSE (1-441): 2.11e-92: 287: 100.00		MTA3_MOUSE (1-577): 0: 626: 63.76
+	Hs
		1031923 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		MTA1_HUMAN (1-668): 0: 672: 55.83
+	Ce
		998284 WDR51_CAEEL (181-441): 5.7e-47: 167: 17.11		EGL27_CAEEL (3-497): 8.2e-110: 358: 20.54
+	Hs
		903576 WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09		RERE_HUMAN (5-663): 1.44e-126: 411: 20.86
+	Hs
		245648 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		RCOR1_HUMAN (145-587): 9.22e-60: 210: 14.79
+	Hs
		1281467 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		RCOR1_HUMAN (145-587): 9.22e-60: 210: 14.79
+	Hs
		1162164 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		MDEAS_HUMAN (139-363): 2.01e-40: 160: 18.78