HitPredict

Interactor 1: EED (Q921E6)
Polycomb protein EED
Gene: EED

Interactor 2: SKP1 (Q9WTX5)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1)
Gene: SKP1

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 441 Mm			1 163
+	Hs
		268012 EED_HUMAN (1-441): 2.11e-92: 287: 100.00		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Hs
		245588 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Mm
		1257397 FBXW7_MOUSE (219-439): 5.6e-28: 118: 15.32		SKP1_MOUSE (1-163): 3.56e-91: 263: 100.00
+	Hs
		929021 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Dm
		285042 FBXW7_DROME (224-441): 2.22e-25: 111: 15.53		O77430_DROME (1-163): 3.96e-82: 240: 76.07
+	Mm
		1131317 FBW1B_MOUSE (160-352): 1.68e-12: 71.3: 18.97		SKP1_MOUSE (1-163): 3.56e-91: 263: 100.00
+	Hs
		929110 FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Ce
		105997 LIN23_CAEEL (160-438): 8.73e-18: 87.9: 20.36		G5EDD8_CAEEL (4-162): 4.74e-67: 203: 60.25