HitPredict

Interactor 1: EED (Q921E6)
Polycomb protein EED
Gene: EED

Interactor 2: BUB3 (Q9WVA3)
Mitotic checkpoint protein BUB3 (WD repeat type I transmembrane protein A72.5)
Gene: BUB3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 441 Mm			1 326
+	Hs
		943879 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		RAE1L_HUMAN (3-325): 4.04e-81: 252: 33.72
+	Dm
		836172 TAF5_DROME (85-367): 9.54e-17: 84.8: 17.48		RAE1_DROME (4-324): 4.39e-92: 279: 35.02
+	Hs
		211260 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		BUB3_HUMAN (1-325): 1.81e-90: 274: 100.00
+	Hs
		245633 TBL1X_HUMAN (13-441): 1.12e-73: 243: 11.39		TBL1R_HUMAN (1-127): 1.12e-26: 111: 21.17
+	Ca
		483033 TUP1_CANAL (4-179): 2.42e-26: 113: 10.38		TUP1_CANAL (1-211): 2.17e-54: 187: 16.81
+	Hs
		1240442 POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29		POC1B_HUMAN (166-324): 9.63e-30: 119: 17.61
+	Sp
		999838 TUP11_SCHPO (360-440): 7.29e-14: 75.7: 18.52		TUP11_SCHPO (1-213): 1.22e-63: 213: 17.90
+	Hs
		1281292 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		FBXW7_HUMAN (1-202): 1.13e-45: 166: 20.38
+	Hs
		1346954 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		NLE1_HUMAN (86-320): 1.28e-49: 173: 13.38
+	Hs
		903418 FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32		WDR5_HUMAN (209-319): 1.16e-19: 89.7: 16.22
+	Hs
		1309163 TBL1Y_HUMAN (277-439): 5.06e-19: 91.1: 13.33		TBL1R_HUMAN (1-127): 1.12e-26: 111: 21.17
+	Mm
		925836 LIS1_MOUSE (332-438): 2.21e-14: 76.5: 18.69		LIS1_MOUSE (167-324): 7.83e-31: 122: 14.56
+	Hs
		792935 LIS1_HUMAN (332-438): 2.37e-14: 76.5: 18.69		LIS1_HUMAN (167-324): 8.93e-31: 121: 14.56
+	Dm
		1358859 FBXW7_DROME (224-441): 2.22e-25: 111: 15.53		WDS_DROME (222-319): 8.22e-18: 84.7: 17.35
+	Dm
		1358845 WDS_DROME (267-440): 1.02e-23: 103: 15.34		WDS_DROME (222-319): 8.22e-18: 84.7: 17.35
+	Hs
		903428 SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29		WDR5_HUMAN (209-319): 1.16e-19: 89.7: 16.22
+	Hs
		903349 WDR5B_HUMAN (279-439): 2.9e-21: 96.1: 12.27		WDR5_HUMAN (209-319): 1.16e-19: 89.7: 16.22
+	Hs
		903551 NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09		WDR5_HUMAN (209-319): 1.16e-19: 89.7: 16.22
+	Hs
		792949 LIS1_HUMAN (332-438): 2.37e-14: 76.5: 18.69		WDR5_HUMAN (209-319): 1.16e-19: 89.7: 16.22