HitPredict

Interactor 1: RHEB (Q921J2)
GTP-binding protein Rheb (Ras homolog enriched in brain) (EC 3.6.5.-)
Gene: RHEB

Interactor 2: RTN4 (Q99P72)
Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein)
Gene: RTN4

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0014069 - postsynaptic density GO:0043025 - neuronal cell body GO:0045202 - synapse GO:0098978 - glutamatergic synapse
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 184 Mm			1 1162
+	Hs
		918953 RAB1A_HUMAN (4-183): 1.64e-78: 234: 30.27		RTN4_HUMAN (1-1162): 1.01e-90: 319: 72.11
+	Hs
		1328148 RAB1B_HUMAN (4-173): 8.56e-78: 232: 30.41		RTN4_HUMAN (1-1162): 1.01e-90: 319: 72.11
+	Hs
		914380 RB11A_HUMAN (4-180): 9.99e-78: 232: 30.34		RTN4_HUMAN (1-1162): 1.01e-90: 319: 72.11
+	Hs
		1079968 RB11B_HUMAN (4-182): 2.56e-77: 231: 31.11		RTN4_HUMAN (1-1162): 1.01e-90: 319: 72.11
+	Hs
		895290 RAB2A_HUMAN (1-173): 1.42e-76: 229: 31.03		RTN4_HUMAN (1-1162): 1.01e-90: 319: 72.11
+	At
		656920 RAE1C_ARATH (4-183): 8.93e-76: 227: 29.12		RTNLD_ARATH (957-1162): 4.89e-71: 239: 21.76
+	Hs
		307017 RB11A_HUMAN (4-180): 9.99e-78: 232: 30.34		RTN3_HUMAN (306-1161): 1.66e-57: 218: 22.22
+	At
		1324948 RAD2B_ARATH (4-177): 1.15e-77: 231: 29.71		RTNLH_ARATH (948-1158): 9.21e-61: 210: 18.89
+	At
		1341181 RABD1_ARATH (1-179): 2.34e-75: 226: 31.32		RTNLL_ARATH (949-1160): 2.1e-48: 172: 17.45
+	Hs
		897894 RAP1B_HUMAN (5-184): 1.1e-37: 129: 38.04		RTN1_HUMAN (405-1162): 1.74e-54: 206: 26.21
+	Hs
		914253 RB11A_HUMAN (4-180): 9.99e-78: 232: 30.34		TITIN_HUMAN (2-1003): 6.42e-13: 76.2: 10.50