HitPredict

Interactor 1: RNF31 (Q924T7)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (Putative Ariadne-like ubiquitin ligase) (PAUL) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31)
Gene: RNF31

Interactor 2: HOIL1 (Q9WUB0)
RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (Heme-oxidized IRP2 ubiquitin ligase 1 homolog) (HOIL-1) (RING-type E3 ubiquitin transferase HOIL-1) (UbcM4-interacting protein 28) (Ubiquitin-conjugating enzyme 7-interacting protein 3)
Gene: Rbck1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.730

The method score is based on:

Property Details
Experiments 21455181, 19136968, 29694895, 24461064, 21455180, 23942237
Identification Methods affinity chromatography technology, pull down, molecular sieving, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0042742 - defense response to bacterium
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
and 5 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1066
Mm

1 508
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Rn
+ At
+ Dm
+ Dm
+ Hs
+ Zm
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024