Interactor 1: SMG7 (Q92540)
Nonsense-mediated mRNA decay factor SMG7 (SMG-7 homolog) (hSMG-7)
Gene: SMG7

Interactor 2: RENT1 (Q92900)
Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)
Gene: UPF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.743

The method score is based on:

Property Details
Experiments 29395067, 31732746, 35271311, 21145460, 20371770, 23348841, 16452507
Identification Methods proximity labelling technology, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006406 - mRNA export from nucleus
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1137
Hs

1 1129
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024