HitPredict

Interactor 1: SMG7 (Q92540)
Nonsense-mediated mRNA decay factor SMG7 (SMG-7 homolog) (hSMG-7)
Gene: SMG7

Interactor 2: SMG1 (Q96Q15)
Serine/threonine-protein kinase SMG1 (SMG-1) (hSMG-1) (EC 2.7.11.1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (Nonsense mediated mRNA decay-associated PI3K-related kinase SMG1)
Gene: SMG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.662

The method score is based on:

Property Details
Experiments 16452507, 29395067, 31732746
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006406 - mRNA export from nucleus
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1137
Hs

1 3661
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024