Interactor 1: SMG7 (Q92540)
Nonsense-mediated mRNA decay factor SMG7 (SMG-7 homolog) (hSMG-7)
Gene: SMG7

Interactor 2: SMG5 (Q9UPR3)
Nonsense-mediated mRNA decay factor SMG5 (EST1-like protein B) (LPTS-RP1) (LPTS-interacting protein) (SMG-5 homolog) (hSMG-5)
Gene: SMG5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 29395067, 23348841
Identification Methods proximity labelling technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EST1~EST1_DNA_bind, EST1_DNA_bind~EST1_DNA_bind
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0005634 - nucleus
GO:0005697 - telomerase holoenzyme complex
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 5 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1137
Hs

1 1016
+ Hs
+ Zm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024