Interactor 1: NICA (Q92542)
Nicastrin
Gene: NCSTN

Interactor 2: APH1A (Q96BI3)
Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha) (Presenilin-stabilization factor)
Gene: APH1A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.751

The method score is based on:

Property Details
Experiments 18667537, 15257293, 14572442, 12471034, 12297508, 19376115, 17911105, 12857757, 15474363, 18201567
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0005769 - early endosome
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
and 17 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 709
Hs

1 265
+ Mm
+ Hs
+ Rn
+ Mm
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024