Interactor 1: TOPB1 (Q92547)
DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)
Gene: TOPBP1

Interactor 2: RAD9A (Q99638)
Cell cycle checkpoint control protein RAD9A (hRAD9) (EC 3.1.11.2) (DNA repair exonuclease rad9 homolog A)
Gene: RAD9A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.759

The method score is based on:

Property Details
Experiments 22925454, 20545769, 30295604, 11395493, 17575048, 25602520, 26088138, 26312135, 25091155, 20724438, 12734188, 12941802, 17006541
Identification Methods affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000076 - DNA replication checkpoint signaling
GO:0000077 - DNA damage checkpoint signaling
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1522
Hs

1 391
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024