Interactor 1: TOPB1 (Q92547)
DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)
Gene: TOPBP1
Interactor 2: BARD1 (Q99728)
BRCA1-associated RING domain protein 1 (BARD-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1)
Gene: BARD1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16391231 |
| Identification Methods | biochemical, affinity chromatography technology |
| Interaction Type | association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BRCT~BRCT, BRCT~PTCB-BRCT |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006281 - DNA repair GO:0006974 - DNA damage response and 2 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
