Interactor 1: APAF (Q7KLI1)
Apoptosome protein Dark (Death-associated APAF1-related killer) (Drosophila Apaf-1 related killer) (Homolog of Apaf-1 and ced-4)
Gene: Dark
Interactor 2: APAF (Q7KLI1)
Apoptosome protein Dark (Death-associated APAF1-related killer) (Drosophila Apaf-1 related killer) (Homolog of Apaf-1 and ced-4)
Gene: Dark
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 0.90 | 0.706 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21220123, unassigned4 |
| Identification Methods | cosedimentation through density gradient, 3D electron microscopy, experimental interaction detection |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | APAF1_C~Dark_WHD, APAF1_C~NB-ARC, Dark_CARD~NB-ARC, Dark_WHD~NB-ARC, NB-ARC~NB-ARC |
| Common GO terms | GO:0002921 - negative regulation of humoral immune response GO:0005198 - structural molecule activity GO:0005524 - ATP binding GO:0006915 - apoptotic process GO:0007291 - sperm individualization and 19 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
