HitPredict

Interactor 1: AP3S1 (Q92572)
AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)
Gene: AP3S1

Interactor 2: RUFY1 (Q96T51)
RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (La-binding protein 1) (Rab4-interacting protein) (Zinc finger FYVE domain-containing protein 12)
Gene: RUFY1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	23144738
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 708
+	Hs
		1302793 AP3M1_HUMAN (1-188): 1.37e-44: 154: 18.09		RUFY1_HUMAN (1-708): 9.63e-73: 251: 100.00
+	Hs
		1302803 AP1M2_HUMAN (3-186): 1.66e-42: 149: 15.76		RUFY1_HUMAN (1-708): 9.63e-73: 251: 100.00
+	Hs
		1123878 AP2M1_HUMAN (1-186): 6.1e-47: 160: 11.83		RUN3A_HUMAN (98-360): 9.2e-62: 215: 25.24
+	Hs
		864080 AP2S1_HUMAN (1-148): 1.73e-43: 143: 40.54		RUN3A_HUMAN (98-360): 9.2e-62: 215: 25.24
+	Hs
		724958 AP2M1_HUMAN (1-186): 6.1e-47: 160: 11.83		MYH9_HUMAN (362-667): 1.39e-14: 80.1: 15.66
+	Ce
		725363 AP2M_CAEEL (1-186): 9.63e-50: 168: 13.98		Q17796_CAEEL (644-696): 4.27e-10: 65.1: 52.73
+	Hs
		1287511 AP2M1_HUMAN (1-186): 6.1e-47: 160: 11.83		MTMR4_HUMAN (580-696): 4.56e-12: 71.6: 29.93