HitPredict

Interactor 1: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Interactor 2: KAT2A (Q92830)
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)
Gene: KAT2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28205554
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001843 - neural tube closure GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0051726 - regulation of cell cycle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1164 Hs			1 837
+	Hs
		999157 CACO1_HUMAN (620-1116): 8.08e-29: 126: 14.93		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		254474 ROCK2_HUMAN (415-1038): 1.55e-24: 113: 11.27		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		148737 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		BPTF_HUMAN (730-830): 2.17e-38: 157: 49.51
+	Hs
		724792 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		725074 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		TRI33_HUMAN (630-836): 1.1e-36: 151: 19.74
+	Hs
		551867 DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54		TRI33_HUMAN (630-836): 1.1e-36: 151: 19.74
+	Hs
		148838 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		BRD3_HUMAN (694-833): 1.21e-33: 140: 25.00
+	Hs
		244025 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		170277 MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43		TIF1A_HUMAN (626-832): 1.23e-44: 176: 22.86
+	Hs
		998661 ROCK1_HUMAN (433-926): 6.18e-15: 82.2: 12.00		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		243875 DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Dm
		1362801 Q9VCC9_DROME (835-1160): 2.53e-09: 63.7: 9.76		NU301_DROME (626-831): 1.2e-38: 158: 27.16
+	Hs
		725147 MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		725269 MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43		TRI33_HUMAN (630-836): 1.1e-36: 151: 19.74
+	Hs
		244394 ROCK1_HUMAN (433-926): 6.18e-15: 82.2: 12.00		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		244610 MYH14_HUMAN (620-918): 1.78e-11: 71.1: 13.11		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Dm
		844320 MYSN_DROME (417-1038): 2.47e-19: 96.8: 9.88		TAF1_DROME (720-831): 1.1e-21: 103: 33.63
+	Hs
		244026 MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		149109 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		PHIP_HUMAN (729-831): 2.23e-15: 83.3: 21.70
+	Hs
		600162 MRCKA_HUMAN (278-842): 4.78e-17: 89.1: 8.78		TAF1_HUMAN (733-831): 8.58e-09: 61.6: 30.30