HitPredict

Interactor 1: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Interactor 2: TARA (Q9H2D6)
TRIO and F-actin-binding protein (Protein Tara) (TRF1-associated protein of 68 kDa) (Trio-associated repeat on actin)
Gene: TRIOBP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21653829
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1164 Hs			1 2365
+	Hs
		1268090 MY18A_HUMAN (461-1064): 4e-25: 115: 10.31		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		725013 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		1167392 MY18A_HUMAN (461-1064): 4e-25: 115: 10.31		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		724884 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		528395 CACO1_HUMAN (620-1116): 8.08e-29: 126: 14.93		MYH6_HUMAN (1655-2365): 7.59e-43: 175: 10.13
+	Hs
		725097 MYH11_HUMAN (392-1122): 2.73e-28: 126: 8.64		MYH10_HUMAN (1444-2225): 5.59e-28: 126: 9.89
+	Hs
		724943 MY18A_HUMAN (461-1064): 4e-25: 115: 10.31		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		724686 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		724687 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		MYH10_HUMAN (1444-2225): 5.59e-28: 126: 9.89
+	Hs
		148460 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		148461 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		MYH10_HUMAN (1444-2225): 5.59e-28: 126: 9.89
+	Hs
		148466 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		MYH11_HUMAN (1483-2225): 1.16e-25: 119: 10.65
+	Hs
		1068617 MY18A_HUMAN (461-1064): 4e-25: 115: 10.31		PLEC_HUMAN (1579-2357): 3.47e-16: 88.1: 12.43
+	Hs
		724839 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		PLEC_HUMAN (1579-2357): 3.47e-16: 88.1: 12.43
+	Hs
		724895 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		MYH14_HUMAN (2035-2363): 1.9e-15: 85.4: 15.06
+	Hs
		148359 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		148818 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		MDC1_HUMAN (88-903): 1.81e-15: 85.4: 14.49
+	Hs
		108763 MY18A_HUMAN (461-1064): 4e-25: 115: 10.31		H0Y2S9_HUMAN (1977-2364): 3.99e-11: 71.2: 17.72
+	Hs
		108759 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		H0Y2S9_HUMAN (1977-2364): 3.99e-11: 71.2: 17.72
+	Hs
		724782 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82