HitPredict

Interactor 1: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Interactor 2: TBCD7 (Q9P0N9)
TBC1 domain family member 7 (Cell migration-inducing protein 23)
Gene: TBC1D7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.723

The method score is based on:

Property Details
Experiments 28561026, 17658474, 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0009267 - cellular response to starvation
GO:0032007 - negative regulation of TOR signaling
GO:0033596 - TSC1-TSC2 complex
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1164
Hs

1 293
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024