HitPredict

Interactor 1: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Interactor 2: NINL (Q9Y2I6)
Ninein-like protein
Gene: NINL

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	28718761, 21653829
Identification Methods	proximity labelling technology, two hybrid, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1164 Hs			1 1382
+	Hs
		1034608 TSC1_HUMAN (1-1164): 0: 725: 100.00		GOGA4_HUMAN (626-1382): 5.37e-22: 106: 10.29
+	Hs
		1051523 DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33		NINL_HUMAN (1-1382): 4.31e-101: 355: 100.00
+	Hs
		1012573 CGNL1_HUMAN (280-1054): 5.93e-34: 144: 11.22		NINL_HUMAN (1-1382): 4.31e-101: 355: 100.00
+	Hs
		1051363 DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33		NIN_HUMAN (744-1382): 1.66e-14: 81.5: 12.90
+	Hs
		725097 MYH11_HUMAN (392-1122): 2.73e-28: 126: 8.64		MYH10_HUMAN (802-1375): 9.91e-23: 108: 10.59
+	Hs
		1012567 CGNL1_HUMAN (280-1054): 5.93e-34: 144: 11.22		NIN_HUMAN (744-1382): 1.66e-14: 81.5: 12.90
+	Hs
		724994 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		CP250_HUMAN (3-995): 1.16e-23: 111: 10.67
+	Hs
		724687 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		MYH10_HUMAN (802-1375): 9.91e-23: 108: 10.59
+	Hs
		528395 CACO1_HUMAN (620-1116): 8.08e-29: 126: 14.93		MYH6_HUMAN (804-1382): 8.3e-18: 92.3: 10.75
+	Hs
		148461 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		MYH10_HUMAN (802-1375): 9.91e-23: 108: 10.59
+	Hs
		724943 MY18A_HUMAN (461-1064): 4e-25: 115: 10.31		MYH9_HUMAN (741-1382): 4.98e-21: 102: 11.79
+	Hs
		148466 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		MYH11_HUMAN (806-1382): 1.58e-22: 107: 10.17
+	Hs
		148769 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		GOGA4_HUMAN (626-1382): 5.37e-22: 106: 10.29
+	Hs
		724686 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		MYH9_HUMAN (741-1382): 4.98e-21: 102: 11.79
+	Hs
		148460 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		MYH9_HUMAN (741-1382): 4.98e-21: 102: 11.79
+	Hs
		1068617 MY18A_HUMAN (461-1064): 4e-25: 115: 10.31		PLEC_HUMAN (42-1041): 9.01e-17: 88.9: 10.67
+	Hs
		724839 MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40		PLEC_HUMAN (42-1041): 9.01e-17: 88.9: 10.67
+	Hs
		148841 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		PLEC_HUMAN (42-1041): 9.01e-17: 88.9: 10.67
+	Hs
		149049 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		NIN_HUMAN (744-1382): 1.66e-14: 81.5: 12.90
+	Hs
		148359 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		DESP_HUMAN (382-835): 1.55e-09: 65.2: 15.40