HitPredict

Interactor 1: MAML1 (Q92585)
Mastermind-like protein 1 (Mam-1)
Gene: MAML1

Interactor 2: SOX7 (Q9BT81)
Transcription factor SOX-7
Gene: SOX7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35016035
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1016 Hs			1 388
+	Hs
		727902 MAML1_HUMAN (1-1016): 2.48e-129: 419: 100.00		SOX6_HUMAN (23-196): 5.35e-37: 144: 28.57
+	Hs
		818308 MAML1_HUMAN (1-1016): 2.48e-129: 419: 100.00		SOX2_HUMAN (9-319): 1.76e-30: 120: 21.77
+	Hs
		1199170 MAML1_HUMAN (1-1016): 2.48e-129: 419: 100.00		PB1_HUMAN (2-155): 3.09e-25: 110: 16.67
+	Hs
		1243837 KMT2C_HUMAN (415-928): 3.16e-13: 76.9: 10.51		SOX7_HUMAN (1-388): 1.8e-48: 170: 100.00
+	Hs
		818226 ANKH1_HUMAN (156-983): 1.46e-28: 126: 13.05		SOX2_HUMAN (9-319): 1.76e-30: 120: 21.77
+	Hs
		1311936 CHD7_HUMAN (288-950): 2.44e-12: 73.8: 10.42		SOX7_HUMAN (1-388): 1.8e-48: 170: 100.00
+	Hs
		818819 KMT2C_HUMAN (415-928): 3.16e-13: 76.9: 10.51		SOX9_HUMAN (30-378): 1.24e-39: 149: 21.11
+	Hs
		727814 CHD7_HUMAN (288-950): 2.44e-12: 73.8: 10.42		SOX5_HUMAN (18-196): 5.2e-39: 150: 29.89
+	Hs
		818841 CHD7_HUMAN (288-950): 2.44e-12: 73.8: 10.42		SOX9_HUMAN (30-378): 1.24e-39: 149: 21.11
+	Hs
		727934 CHD7_HUMAN (288-950): 2.44e-12: 73.8: 10.42		SOX6_HUMAN (23-196): 5.35e-37: 144: 28.57
+	Hs
		239438 MAGC1_HUMAN (103-883): 1.15e-19: 97.3: 11.52		SOX2_HUMAN (9-319): 1.76e-30: 120: 21.77
+	Hs
		818266 KMT2C_HUMAN (415-928): 3.16e-13: 76.9: 10.51		SOX2_HUMAN (9-319): 1.76e-30: 120: 21.77
+	Hs
		818550 CHD7_HUMAN (288-950): 2.44e-12: 73.8: 10.42		SOX2_HUMAN (9-319): 1.76e-30: 120: 21.77
+	Hs
		817983 BPTF_HUMAN (342-959): 6.75e-12: 72.5: 14.33		SOX2_HUMAN (9-319): 1.76e-30: 120: 21.77
+	Hs
		818458 TARA_HUMAN (47-987): 2.2e-11: 70.7: 9.85		SOX2_HUMAN (9-319): 1.76e-30: 120: 21.77
+	Hs
		881831 CHD7_HUMAN (288-950): 2.44e-12: 73.8: 10.42		SOX10_HUMAN (30-386): 4.56e-28: 116: 24.14
+	Hs
		1243843 KMT2C_HUMAN (415-928): 3.16e-13: 76.9: 10.51		SOX17_HUMAN (5-350): 4.93e-27: 112: 34.15
+	Hs
		1332326 CHD7_HUMAN (288-950): 2.44e-12: 73.8: 10.42		SOX17_HUMAN (5-350): 4.93e-27: 112: 34.15
+	Hs
		1199209 CHD7_HUMAN (288-950): 2.44e-12: 73.8: 10.42		PB1_HUMAN (2-155): 3.09e-25: 110: 16.67
+	Mm
		1351630 PCLO_MOUSE (270-1011): 5.28e-22: 105: 9.93		PCLO_MOUSE (119-346): 1.28e-11: 68.6: 8.77