Interactor 1: EDEM1 (Q92611)
ER degradation-enhancing alpha-mannosidase-like protein 1
Gene: EDEM1

Interactor 2: MA1B1 (Q9UKM7)
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Man9GlcNAc2-specific-processing alpha-mannosidase) (Mannosidase alpha class 1B member 1)
Gene: MAN1B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 32423001
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Glyco_hydro_47~Glyco_hydro_47
Common GO terms GO:0004571 - mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006058 - mannoprotein catabolic process
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 657
Hs

1 699
+ Hs
+ Hs
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024