HitPredict

Interactor 1: JADE3 (Q92613)
Protein Jade-3 (Jade family PHD finger protein 3) (PHD finger protein 16)
Gene: JADE3

Interactor 2: BRPF3 (Q9ULD4)
Bromodomain and PHD finger-containing protein 3
Gene: BRPF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD_2~zf-HC5HC2H_2, zf-HC5HC2H_2~zf-HC5HC2H_2
Common GO terms	GO:0000123 - histone acetyltransferase complex GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 823 Hs			1 1205
+	Hs
		1152695 JADE1_HUMAN (1-798): 0: 677: 43.85		BRPF3_HUMAN (1-1205): 0: 999: 100.00
+	Hs
		876709 JADE3_HUMAN (1-823): 0: 829: 100.00		BRPF1_HUMAN (1-1202): 0: 813: 48.20
+	Hs
		1343286 JADE2_HUMAN (2-788): 0: 634: 39.93		BRPF3_HUMAN (1-1205): 0: 999: 100.00
+	Hs
		876697 JADE1_HUMAN (1-798): 0: 677: 43.85		BRPF1_HUMAN (1-1202): 0: 813: 48.20
+	Hs
		876722 JADE2_HUMAN (2-788): 0: 634: 39.93		BRPF1_HUMAN (1-1202): 0: 813: 48.20
+	Hs
		319375 BRD1_HUMAN (40-580): 2.3e-123: 398: 26.14		BRPF3_HUMAN (1-1205): 0: 999: 100.00
+	Hs
		319154 BRD1_HUMAN (40-580): 2.3e-123: 398: 26.14		BRPF1_HUMAN (1-1202): 0: 813: 48.20
+	Hs
		1152685 JADE3_HUMAN (1-823): 0: 829: 100.00		JADE1_HUMAN (6-632): 1.24e-105: 354: 24.73
+	Hs
		1268052 JADE3_HUMAN (1-823): 0: 829: 100.00		JADE2_HUMAN (10-602): 3.25e-91: 313: 23.58
+	Hs
		319287 JADE3_HUMAN (1-823): 0: 829: 100.00		BRD1_HUMAN (680-1202): 1.71e-77: 279: 28.32
+	Hs
		1152693 JADE1_HUMAN (1-798): 0: 677: 43.85		JADE2_HUMAN (10-602): 3.25e-91: 313: 23.58
+	Hs
		319230 JADE1_HUMAN (1-798): 0: 677: 43.85		BRD1_HUMAN (680-1202): 1.71e-77: 279: 28.32
+	Hs
		1067074 JADE3_HUMAN (1-823): 0: 829: 100.00		BRD3_HUMAN (568-882): 4.36e-28: 124: 12.30
+	Hs
		319344 JADE2_HUMAN (2-788): 0: 634: 39.93		BRD1_HUMAN (680-1202): 1.71e-77: 279: 28.32