HitPredict

Interactor 1: MY18A (Q92614)
Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
Gene: MYO18A

Interactor 2: MRCKB (Q9Y5S2)
Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)
Gene: CDC42BPB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26496610, 18854160
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0016477 - cell migration GO:0031032 - actomyosin structure organization GO:0042641 - actomyosin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2054 Hs			1 1711
+	Hs
		149126 MY18A_HUMAN (1-2054): 0: 1279: 100.00		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		148460 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		725010 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		SIK2_HUMAN (60-810): 1.3e-120: 405: 16.86
+	Hs
		528359 MYH6_HUMAN (1141-2053): 1.27e-51: 204: 13.34		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		725079 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		ST38L_HUMAN (1-421): 5.35e-120: 388: 37.93
+	Hs
		568567 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		KAPCA_HUMAN (48-375): 1.99e-119: 382: 34.72
+	Hs
		148466 MYH11_HUMAN (1684-2053): 3.04e-19: 97.5: 15.00		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		522538 MYH1_HUMAN (959-1794): 5.17e-37: 156: 9.50		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		610802 MYH4_HUMAN (976-1822): 6.83e-37: 155: 13.06		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		148461 MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		610795 MYH2_HUMAN (1056-1724): 7.97e-34: 145: 11.11		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		148991 MYH14_HUMAN (1253-1933): 3.46e-11: 71.2: 19.08		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		728513 MYH11_HUMAN (1684-2053): 3.04e-19: 97.5: 15.00		SIK2_HUMAN (60-810): 1.3e-120: 405: 16.86
+	Hs
		725242 MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56		SIK2_HUMAN (60-810): 1.3e-120: 405: 16.86
+	Hs
		568568 MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56		KAPCA_HUMAN (48-375): 1.99e-119: 382: 34.72
+	Hs
		1189798 MYH14_HUMAN (1253-1933): 3.46e-11: 71.2: 19.08		SIK2_HUMAN (60-810): 1.3e-120: 405: 16.86
+	Mm
		949400 MYO5A_MOUSE (1600-2052): 2.08e-24: 114: 12.04		TNIK_MOUSE (52-836): 1.02e-93: 335: 13.91
+	Dm
		1213452 Q8INC3_DROME (1049-1774): 1.52e-37: 157: 10.90		WARTS_DROME (66-381): 5.73e-70: 259: 40.00
+	Dm
		1001877 Q0KI67_DROME (1049-1774): 6.82e-37: 155: 10.90		WARTS_DROME (66-381): 5.73e-70: 259: 40.00
+	Hs
		724810 MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96		ROCK1_HUMAN (360-1074): 6.44e-17: 89.6: 13.02