HitPredict

Interactor 1: LAR4B (Q92615)
La-related protein 4B (La ribonucleoprotein domain family member 4B) (La ribonucleoprotein domain family member 5) (La-related protein 5)
Gene: LARP4B

Interactor 2: YTHD1 (Q9BYJ9)
YTH domain-containing family protein 1 (DF1) (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1)
Gene: YTHDF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0010494 - cytoplasmic stress granule GO:0045727 - positive regulation of translation
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 738 Hs			1 559
+	Hs
		1268204 LAR4B_HUMAN (1-738): 0: 654: 100.00		YTHD2_HUMAN (1-558): 1.49e-138: 415: 62.72
+	Hs
		1192346 LAR4B_HUMAN (1-738): 0: 654: 100.00		YTHD3_HUMAN (1-541): 4.01e-131: 396: 65.91
+	Hs
		1174847 LARP4_HUMAN (50-738): 1.65e-168: 503: 36.78		YTHD1_HUMAN (1-559): 2.02e-141: 422: 100.00
+	Hs
		1174879 LARP4_HUMAN (50-738): 1.65e-168: 503: 36.78		YTHD2_HUMAN (1-558): 1.49e-138: 415: 62.72
+	Hs
		1174812 LARP4_HUMAN (50-738): 1.65e-168: 503: 36.78		YTHD3_HUMAN (1-541): 4.01e-131: 396: 65.91
+	Hs
		1268147 LAR4B_HUMAN (1-738): 0: 654: 100.00		YTDC1_HUMAN (301-554): 6.03e-45: 171: 22.22
+	At
		1275967 LRP1A_ARATH (38-266): 1.12e-39: 159: 22.71		Q9FPE7_ARATH (145-559): 1.58e-96: 305: 32.86
+	Hs
		1116549 LARP7_HUMAN (154-461): 2.7e-44: 170: 15.43		YTDC2_HUMAN (226-535): 2.61e-51: 192: 23.18
+	Hs
		1116465 LARP7_HUMAN (154-461): 2.7e-44: 170: 15.43		YTDC1_HUMAN (301-554): 6.03e-45: 171: 22.22
+	Hs
		1116598 LARP7_HUMAN (154-461): 2.7e-44: 170: 15.43		CHD7_HUMAN (14-322): 4.11e-10: 65: 14.24