HitPredict

Interactor 1: GCN1 (Q92616)
Stalled ribosome sensor GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)
Gene: GCN1

Interactor 2: NRBP2 (Q9NSY0)
Nuclear receptor-binding protein 2 (Transformation-related gene 16 protein) (TRG-16)
Gene: NRBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2671 Hs			1 501
+	Hs
		1026197 GCN1_HUMAN (1-2671): 0: 2129: 100.00		PAK1_HUMAN (4-317): 4.56e-76: 250: 23.57
+	Rn
		102516 G3V7T6_RAT (1238-2069): 1.02e-61: 236: 13.97		AAPK1_RAT (37-476): 4.69e-99: 311: 15.25
+	Mm
		682128 MTOR_MOUSE (824-2632): 2.47e-34: 147: 12.66		AKT1_MOUSE (9-367): 2.44e-119: 360: 14.63
+	Hs
		127393 IPO5_HUMAN (1381-2409): 4.59e-37: 155: 12.18		KS6B2_HUMAN (17-415): 1.16e-115: 351: 15.63
+	Hs
		681713 MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46		AKT1_HUMAN (9-367): 5.98e-119: 359: 14.63
+	Hs
		787595 MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46		KS6B2_HUMAN (17-415): 1.16e-115: 351: 15.63
+	Mm
		1207224 MTOR_MOUSE (824-2632): 2.47e-34: 147: 12.66		KS6B1_MOUSE (1-476): 1.19e-114: 350: 14.81
+	Hs
		127253 IPO5_HUMAN (1381-2409): 4.59e-37: 155: 12.18		STK4_HUMAN (14-500): 1.5e-111: 340: 14.89
+	At
		1104833 2AAA_ARATH (947-1565): 3.62e-27: 121: 13.69		CIPKG_ARATH (25-494): 1.15e-118: 358: 13.15
+	Hs
		672414 2AAB_HUMAN (2265-2670): 2.67e-36: 149: 14.67		AAPK1_HUMAN (37-476): 4.17e-99: 311: 15.25
+	Hs
		787468 MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46		AAPK1_HUMAN (37-476): 4.17e-99: 311: 15.25
+	Hs
		672006 2AAA_HUMAN (959-1405): 1.51e-19: 97.8: 12.22		AKT1_HUMAN (9-367): 5.98e-119: 359: 14.63
+	Hs
		672185 2AAA_HUMAN (959-1405): 1.51e-19: 97.8: 12.22		MARK2_HUMAN (11-490): 6.7e-115: 358: 13.73
+	Hs
		672244 2AAA_HUMAN (959-1405): 1.51e-19: 97.8: 12.22		MARK4_HUMAN (9-494): 3.47e-114: 355: 13.62
+	Hs
		672336 2AAA_HUMAN (959-1405): 1.51e-19: 97.8: 12.22		KS6B2_HUMAN (17-415): 1.16e-115: 351: 15.63
+	Hs
		1023075 CAND1_HUMAN (1460-2587): 2.11e-22: 108: 13.92		STK4_HUMAN (14-500): 1.5e-111: 340: 14.89
+	Hs
		672056 2AAA_HUMAN (959-1405): 1.51e-19: 97.8: 12.22		SIK1_HUMAN (37-492): 4.97e-109: 343: 15.92
+	Dm
		734194 2AAA_DROME (959-1395): 6.8e-14: 79.7: 11.39		AKT1_DROME (7-374): 6.23e-117: 358: 13.76
+	Hs
		1023040 CKAP5_HUMAN (953-1968): 8.99e-11: 70.1: 10.33		STK4_HUMAN (14-500): 1.5e-111: 340: 14.89