HitPredict

Interactor 1: GCN1 (Q92616)
Stalled ribosome sensor GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)
Gene: GCN1

Interactor 2: SCN3B (Q9NY72)
Sodium channel regulatory subunit beta-3
Gene: SCN3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2671 Hs			1 215
+	Hs
		246374 GCN1_HUMAN (1-2671): 0: 2129: 100.00		SCN2B_HUMAN (5-215): 2.23e-52: 169: 20.83
+	Hs
		246354 Q4LE60_HUMAN (1189-2014): 7.32e-59: 225: 12.28		SCN2B_HUMAN (5-215): 2.23e-52: 169: 20.83
+	Hs
		787587 MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46		SCN3B_HUMAN (1-215): 2.12e-69: 213: 100.00
+	Hs
		1117733 Q4LE60_HUMAN (1189-2014): 7.32e-59: 225: 12.28		VSIG1_HUMAN (7-165): 1.46e-33: 125: 20.37
+	Hs
		1117739 Q4LE60_HUMAN (1189-2014): 7.32e-59: 225: 12.28		VSIG2_HUMAN (10-164): 1.21e-32: 121: 19.88
+	Hs
		1273203 TNPO1_HUMAN (908-1705): 1.2e-50: 198: 13.59		VSIG2_HUMAN (10-164): 1.21e-32: 121: 19.88
+	Hs
		246339 MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46		SCN2B_HUMAN (5-215): 2.23e-52: 169: 20.83
+	Hs
		787545 MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46		VSIG2_HUMAN (10-164): 1.21e-32: 121: 19.88