HitPredict

Interactor 1: ZN516 (Q92618)
Zinc finger protein 516
Gene: ZNF516

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	35271311, 28947780
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1163 Hs			1 488
+	Hs
		1038587 ZN516_HUMAN (1-1163): 0: 1179: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		167156 ZN536_HUMAN (25-590): 1.04e-85: 306: 37.15		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		260391 ZN217_HUMAN (169-600): 3.48e-51: 199: 33.95		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		260378 ZN217_HUMAN (169-600): 3.48e-51: 199: 33.95		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1270492 ZN219_HUMAN (36-314): 2.6e-30: 130: 31.65		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Mm
		93753 ZN431_MOUSE (22-298): 1.26e-13: 77: 25.44		HDAC2_MOUSE (1-488): 0: 704: 99.39
+	Hs
		1038772 ZN219_HUMAN (36-314): 2.6e-30: 130: 31.65		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Mm
		93752 ZN431_MOUSE (22-298): 1.26e-13: 77: 25.44		HDAC1_MOUSE (1-443): 0: 645: 90.29