HitPredict

Interactor 1: ANS1A (Q92625)
Ankyrin repeat and SAM domain-containing protein 1A (Odin)
Gene: ANKS1A

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1, Ank_2~SH3_9
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1134 Hs			1 639
+	Hs
		1268487 ANS1A_HUMAN (1-1134): 0: 792: 100.00		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		1191815 ANS1B_HUMAN (1-1101): 0: 593: 33.52		CD2AP_HUMAN (1-639): 9.29e-139: 420: 100.00
+	Hs
		235561 ANS1A_HUMAN (1-1134): 0: 792: 100.00		VINEX_HUMAN (163-343): 4.52e-13: 74.2: 18.28
+	Hs
		209098 ANS1B_HUMAN (1-1101): 0: 593: 33.52		NCK2_HUMAN (2-361): 2.2e-59: 205: 16.17
+	Mm
		1206665 ANS1B_MOUSE (1-1133): 0: 621: 33.57		SRGP2_MOUSE (2-443): 2.8e-44: 172: 11.52
+	Mm
		1206687 ANS1B_MOUSE (1-1133): 0: 621: 33.57		ARHG7_MOUSE (230-378): 9.82e-13: 73.4: 26.17
+	Mm
		1206702 ANS1B_MOUSE (1-1133): 0: 621: 33.57		ITSN1_MOUSE (1-55): 4.64e-10: 65.3: 41.82
+	Hs
		1115812 Q49AR9_HUMAN (675-1134): 2.78e-116: 374: 92.70		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		1263386 CSKI2_HUMAN (1-592): 3.95e-69: 255: 24.71		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		209131 CSKI2_HUMAN (1-592): 3.95e-69: 255: 24.71		NCK2_HUMAN (2-361): 2.2e-59: 205: 16.17
+	Hs
		235513 Q49AR9_HUMAN (675-1134): 2.78e-116: 374: 92.70		VINEX_HUMAN (163-343): 4.52e-13: 74.2: 18.28
+	Hs
		557753 CSKI2_HUMAN (1-592): 3.95e-69: 255: 24.71		NCK1_HUMAN (113-378): 9.79e-21: 96.5: 14.24
+	Hs
		924484 ANK2_HUMAN (180-837): 1.86e-34: 146: 13.55		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Dm
		1360790 TNKS_DROME (147-289): 4.1e-10: 66.2: 35.86		Q9VA36_DROME (4-395): 1.02e-46: 179: 26.40
+	Hs
		557660 ANK2_HUMAN (180-837): 1.86e-34: 146: 13.55		NCK1_HUMAN (113-378): 9.79e-21: 96.5: 14.24
+	Hs
		1078859 MIB1_HUMAN (3-343): 1.07e-41: 168: 22.32		ITSN1_HUMAN (1-55): 3.97e-11: 68.8: 43.64
+	Ce
		1274646 Q93203_CAEEL (4-167): 2.13e-18: 93.3: 18.33		Q9U2T9_CAEEL (27-492): 3.56e-11: 68.5: 13.89
+	Hs
		257713 ANR17_HUMAN (2-102): 1.08e-14: 81.7: 23.76		ITSN2_HUMAN (1-63): 2.7e-12: 72.2: 34.92