HitPredict

Interactor 1: PXDN (Q92626)
Peroxidasin homolog (EC 1.11.2.-) (Melanoma-associated antigen MG50) (Peroxidasin 1) (hsPxd01) (Vascular peroxidase 1) (p53-responsive gene 2 protein) [Cleaved into: PXDN active fragment]
Gene: PXDN

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.633

Property	Details
Experiments	30833792, 32409323, 33961781, 22268729
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1479 Hs			1 293
+	Hs
		1268546 PXDN_HUMAN (1-1479): 0: 1460: 100.00		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		613168 PGH1_HUMAN (903-1309): 1.5e-103: 345: 20.00		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1344696 DUOX1_HUMAN (727-1300): 1.01e-126: 433: 24.37		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		299591 LRIG2_HUMAN (3-712): 9.31e-62: 233: 16.37		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1356264 ROBO1_HUMAN (310-1017): 1.82e-78: 289: 17.50		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		299598 LRIG2_HUMAN (3-712): 9.31e-62: 233: 16.37		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1166672 LRIG3_HUMAN (2-203): 6.4e-33: 141: 25.87		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1294959 LRIG1_HUMAN (1-212): 1.61e-24: 113: 21.51		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17