HitPredict

Interactor 1: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19287380
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 601 Hs			1 449
+	Hs
		625584 CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		969108 KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		1047627 CDK13_HUMAN (3-598): 8.85e-117: 381: 19.87		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		625344 CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		933442 CDK13_HUMAN (3-598): 8.85e-117: 381: 19.87		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		933175 KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		1047611 CDK13_HUMAN (3-598): 8.85e-117: 381: 19.87		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		428148 KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		428202 CDK13_HUMAN (3-598): 8.85e-117: 381: 19.87		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		933762 KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		933805 CDK13_HUMAN (3-598): 8.85e-117: 381: 19.87		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		414682 CDK1_HUMAN (219-538): 9.81e-126: 373: 27.13		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		428196 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		933800 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		833979 CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56		TBA8_HUMAN (1-439): 0: 698: 90.66