HitPredict

Interactor 1: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Interactor 2: NDEL1 (Q9GZM8)
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)
Gene: NDEL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	32707033
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 601 Hs			1 345
+	Hs
		1268599 DYRK2_HUMAN (1-601): 0: 534: 100.00		NDE1_HUMAN (3-321): 2.95e-41: 149: 55.25
+	Hs
		1268587 DYRK2_HUMAN (1-601): 0: 534: 100.00		KIFC1_HUMAN (12-245): 7e-23: 101: 16.24
+	Hs
		415055 CDK1_HUMAN (219-538): 9.81e-126: 373: 27.13		NDEL1_HUMAN (1-345): 1.8e-67: 217: 100.00
+	Hs
		960327 CDK5_HUMAN (219-541): 2.4e-116: 349: 27.49		NDEL1_HUMAN (1-345): 1.8e-67: 217: 100.00
+	Hs
		148173 DYRK3_HUMAN (13-601): 3.18e-149: 444: 58.88		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		1044228 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		EP15R_HUMAN (7-325): 7e-42: 157: 12.81
+	Hs
		415084 CDK1_HUMAN (219-538): 9.81e-126: 373: 27.13		NDE1_HUMAN (3-321): 2.95e-41: 149: 55.25
+	Hs
		625176 CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		625177 CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71		MYH10_HUMAN (2-228): 6.16e-23: 102: 18.06
+	Hs
		625491 CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71		CYTSA_HUMAN (2-331): 7.36e-23: 102: 16.06
+	Hs
		415074 CDK1_HUMAN (219-538): 9.81e-126: 373: 27.13		MYO10_HUMAN (36-324): 1.73e-29: 121: 15.92
+	Hs
		1044170 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		MYO10_HUMAN (36-324): 1.73e-29: 121: 15.92
+	Hs
		724784 KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70		MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57
+	Hs
		148286 CDK1_HUMAN (219-538): 9.81e-126: 373: 27.13		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		728476 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		MYH11_HUMAN (2-223): 2.17e-26: 112: 18.92
+	Hs
		148781 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32
+	Hs
		1043869 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		CYTSA_HUMAN (2-331): 7.36e-23: 102: 16.06
+	Hs
		725159 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		MYH10_HUMAN (2-228): 6.16e-23: 102: 18.06
+	Hs
		1044290 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		ICE1_HUMAN (11-277): 4.04e-22: 99.7: 15.83
+	Hs
		1377199 DYR1B_HUMAN (149-537): 1.88e-118: 366: 39.11		ICE1_HUMAN (11-277): 4.04e-22: 99.7: 15.83