HitPredict

Interactor 1: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Interactor 2: NDE1 (Q9NXR1)
Nuclear distribution protein nudE homolog 1 (NudE)
Gene: NDE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 601 Hs			1 335
+	Hs
		1268590 DYRK2_HUMAN (1-601): 0: 534: 100.00		NDEL1_HUMAN (3-316): 1.44e-65: 212: 56.78
+	Hs
		415084 CDK1_HUMAN (219-538): 9.81e-126: 373: 27.13		NDE1_HUMAN (1-335): 2.68e-70: 224: 100.00
+	Hs
		415055 CDK1_HUMAN (219-538): 9.81e-126: 373: 27.13		NDEL1_HUMAN (3-316): 1.44e-65: 212: 56.78
+	Hs
		528401 CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71		MYH8_HUMAN (3-226): 2.41e-33: 132: 12.95
+	Hs
		625176 CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71		MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18
+	Hs
		522542 CDK3_HUMAN (219-542): 1.22e-134: 396: 27.80		MYH1_HUMAN (3-226): 1.26e-35: 139: 13.84
+	Hs
		960129 CDK3_HUMAN (219-542): 1.22e-134: 396: 27.80		MYH13_HUMAN (3-243): 1.12e-35: 139: 12.03
+	Hs
		522604 CDK3_HUMAN (219-542): 1.22e-134: 396: 27.80		MYH7_HUMAN (3-226): 2.27e-35: 138: 12.95
+	Hs
		960128 CDK3_HUMAN (219-542): 1.22e-134: 396: 27.80		MYH2_HUMAN (3-226): 2.96e-35: 138: 14.29
+	Hs
		625177 CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71		MYH10_HUMAN (2-205): 2.43e-27: 115: 20.10
+	Hs
		502908 CDK3_HUMAN (219-542): 1.22e-134: 396: 27.80		MYH3_HUMAN (3-235): 1.67e-33: 133: 12.88
+	Hs
		528405 CDK3_HUMAN (219-542): 1.22e-134: 396: 27.80		MYH8_HUMAN (3-226): 2.41e-33: 132: 12.95
+	Hs
		528368 CDK3_HUMAN (219-542): 1.22e-134: 396: 27.80		MYH6_HUMAN (3-226): 3.52e-33: 131: 13.39
+	Hs
		728476 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		MYH11_HUMAN (9-205): 2.12e-42: 158: 19.80
+	Mm
		554927 KPCE_MOUSE (55-510): 2.32e-124: 385: 16.70		MYH7_MOUSE (3-226): 5.28e-35: 137: 12.95
+	Mm
		554901 KPCE_MOUSE (55-510): 2.32e-124: 385: 16.70		MYH6_MOUSE (3-226): 2.48e-33: 132: 13.39
+	Hs
		787910 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		724784 KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70		MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18
+	Hs
		528372 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		MYH6_HUMAN (3-226): 3.52e-33: 131: 13.39
+	Hs
		725159 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		MYH10_HUMAN (2-205): 2.43e-27: 115: 20.10