HitPredict

Interactor 1: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Interactor 2: BCLF1 (Q9NYF8)
Bcl-2-associated transcription factor 1 (Btf) (BCLAF1 and THRAP3 family member 1)
Gene: BCLAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	32707033
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006974 - DNA damage response
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 601 Hs			1 920
+	Hs
		625615 CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71		BCLF1_HUMAN (56-920): 2.97e-109: 360: 100.00
+	Hs
		969115 KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70		BCLF1_HUMAN (56-920): 2.97e-109: 360: 100.00
+	Hs
		1044201 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		BCLF1_HUMAN (56-920): 2.97e-109: 360: 100.00
+	Hs
		969120 KPCE_HUMAN (55-510): 3.31e-123: 382: 16.70		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		1044295 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		1264773 DYRK2_HUMAN (1-601): 0: 534: 100.00		TITIN_HUMAN (94-778): 5.89e-11: 69.2: 8.45
+	Hs
		833824 CLK1_HUMAN (204-535): 3.1e-62: 215: 35.80		BCLF1_HUMAN (56-920): 2.97e-109: 360: 100.00
+	Hs
		833980 CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56		BCLF1_HUMAN (56-920): 2.97e-109: 360: 100.00
+	Hs
		833761 CLK1_HUMAN (204-535): 3.1e-62: 215: 35.80		RBBP6_HUMAN (3-913): 8.4e-79: 282: 14.05
+	Hs
		69425 CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71		B0AZU3_HUMAN (783-920): 5.5e-16: 77.7: 100.00
+	Hs
		1191723 CLK4_HUMAN (204-535): 1.85e-59: 207: 33.71		RBBP6_HUMAN (3-913): 8.4e-79: 282: 14.05
+	Hs
		625528 CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71		TITIN_HUMAN (94-778): 5.89e-11: 69.2: 8.45
+	Hs
		833842 CLK1_HUMAN (204-535): 3.1e-62: 215: 35.80		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Hs
		833911 CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56		RBBP6_HUMAN (3-913): 8.4e-79: 282: 14.05
+	Hs
		833996 CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56		TR150_HUMAN (46-920): 4.85e-76: 269: 33.00
+	Ce
		246633 MBK2_CAEEL (95-577): 9.79e-125: 388: 60.46		O61201_CAEEL (117-779): 4.88e-10: 66.2: 14.35
+	Hs
		1044321 DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52		PCLO_HUMAN (96-875): 9.08e-13: 75: 10.41