HitPredict

Interactor 1: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Interactor 2: DCAF1 (Q9Y4B6)
DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein)
Gene: DCAF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.720

The method score is based on:

Property Details
Experiments 28242748, 32707033, 19287380, 29507117, 30590706
Identification Methods affinity chromatography technology, proximity labelling technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0106310 - protein serine kinase activity
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 601
Hs

1 1507
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024