HitPredict

Interactor 1: LPAR1 (Q92633)
Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2)
Gene: LPAR1

Interactor 2: TTYH3 (Q9C0H2)
Protein tweety homolog 3 (hTTY3) (Volume-regulated anion channel subunit TTYH3)
Gene: TTYH3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 364 Hs			1 523
+	Hs
		328387 S1PR4_HUMAN (1-360): 9.27e-72: 230: 30.89		TTYH3_HUMAN (1-523): 0: 764: 100.00
+	Hs
		666347 NK3R_HUMAN (13-364): 1.05e-63: 211: 15.85		TTYH3_HUMAN (1-523): 0: 764: 100.00
+	Hs
		1319361 LPAR2_HUMAN (23-364): 1.03e-59: 197: 53.06		TTYH3_HUMAN (1-523): 0: 764: 100.00
+	Hs
		598776 S1PR1_HUMAN (10-333): 3.19e-59: 197: 36.86		TTYH3_HUMAN (1-523): 0: 764: 100.00
+	Hs
		598772 S1PR1_HUMAN (10-333): 3.19e-59: 197: 36.86		TTYH2_HUMAN (2-513): 0: 630: 40.58
+	Hs
		1268651 LPAR1_HUMAN (1-364): 3.44e-73: 233: 100.00		TTYH1_HUMAN (6-416): 9.68e-165: 476: 39.37
+	Hs
		1329924 LPAR3_HUMAN (22-354): 9.16e-73: 231: 50.75		TTYH1_HUMAN (6-416): 9.68e-165: 476: 39.37
+	Hs
		304728 S1PR2_HUMAN (28-350): 3.48e-70: 225: 32.92		TTYH1_HUMAN (6-416): 9.68e-165: 476: 39.37
+	Hs
		1329002 S1PR5_HUMAN (16-354): 9.69e-69: 222: 31.23		TTYH1_HUMAN (6-416): 9.68e-165: 476: 39.37